Cytokeratin AE1+AE3 , AE1+AE3 , IgG1 - 1ml

Part Number - PAA-MOB 190

Monoclonal Mouse Antibody to Human Cytokeratin AE1/AE3 F, P/H Catalog No.: Mob 190 Concentrated 1ml Mob 190-05 Concentrated 0.5ml PDM 072 Prediluted 6ml Immunogen: BALB/C mice were immunized with human epidermal keratin.
Clone: AE1 + AE3 Isotype: AE1, IgG1, kappa; AE3, IgG1, kappa Positive Control: Skin Cellular Localization: Cytoplasmic Specificity: This AE1/AE3 antibody cocktail recognizes most of the acidic (Type I) keratins as well as basic (Type II).
It recognizes keratin polypeptides of 40, 48, 50, 52, 54, 56.5, 58, 59 and 64 to 67 kDa.
In keratinized epidermis, 50 kDa keratin is present in the basal layer, while 56.5 kDa keratin is present in suprabasal layers.
58 kDa keratin is present in the basal and suprabasal layers, while 65 to 67 kDa keratin is present in the cells above the basal layers.
This antibody can be used to stain distinct cell layers in an epithelial tissue and various neoplasms of epithelial origin.
F=Frozen P=Formalin Fixed Paraffin Embedded H=Heat Induced Pretreatment E=Enzyme Pretreatment For more information please visit the DBS website at dbiosys.com